New homologues and metabolites of chemicals: stimulants, dissociatives, benzodiazepines, sedatives, tranquilizers, opioids, analgesics, tryptamines, psychedelics, indazoles, benzazoles
Articles about chemicals, news in the world of chemistry, news about new chemical developments, articles about new homologues, news about metabolites
The Dutch Senate has approved a bill banning hundreds of types of so-called designer drugs. The law came into force on July 1. According to the NRC newspaper, until now, manufacturers of designer drugs have managed to circumvent the law and bring a narcotic substance to the market, only slightly changing its composition so thatRead More
This group consists of chemical compounds that, being antagonists of NMDA receptors, interfere with the signaling relationships of various parts of the brain. The resulting dissociation of internal and external signals is due to the uncompetitive blocking of the effects of glutamic acid, more precisely glutamate anions, which are the main excitatory neurotransmitter for ionotropicRead More
Benzodiazepines – a list of drugs and their effects. What to do in case of poisoning and intoxication? What is the most effective antidote? We will talk about the narcotic effect of benzodiazepines, as well as analyze the mechanism of action of the drugs. This is the name of a group of psychotropic drugs thatRead More
Antidepressants combine a large group of drugs, the main property of which is the elimination of a depressive state. Antidepressants include MAO inhibitors: hydrazine (iprazide, nialamide) and nonhydrazine derivatives (indopan, etc.), 4- and 3-cyclic compounds (mianserin, imipramine, amitriptyline, azafen, pyrazidol), secondary amines (desipramine). There is also a group of antidepressants of the second generation (nomifenzyl,Read More
Neuroleptics – drugs for the treatment of mental disorders Neuroleptics are representatives of a large class of psychotropic drugs. The latter have a selective effect on the human psyche, i.e. on his thinking and emotions. Neuroleptics, in turn, slow down neuropsychiatric processes and calm a person. However, if these antipsychotic drugs are prescribed to aRead More
Sometimes pharmaceuticals developed for noble purposes become the object of attention of fans of “acute” sensations. This also happened with the phenylalkylamine derivative, used in a number of countries for the treatment of narcolepsy (a state of drowsiness that worries during the day), apathy, depression, asthenia. Amphetamine-based drugs are still being used for strict indicationsRead More
Many drugs containing amphetamine and its derivatives are synthesized in shadow laboratories. MDMA and MDA are considered the most common. Most ecstasy analogues are psychoactive amphetamine-type compounds that affect the central and peripheral adrenergic receptors. The general picture of poisoning is identical, but the manifestation of clinical features is possible. MDMA analogues MDMA is partRead More
Dissociative substances are a class of hallucinogens that distort the perception of sight and sound. Dissociatives also cause a sense of detachment from the environment and from oneself. Initially, they were developed as an analgesic for general use in surgery. The effects of these substances are diverse, most often unpleasant. But the experience gained fromRead More
“Phencyclidine” belongs to the group of hallucinogens. The main feature of these narcotic drugs is to completely change the nature of the consumer’s thinking and mood. They do not act immediately on the central nervous system in such a way that they cause its overexcitation towards euphoria, sometimes into a state of severe depression orRead More
Parkopan (cyclodol, trihexyphenidyl, parkinsan, romparkin, parkopan, anti-spas, antitrem, aparkan, artane, benzhexol hydrochloride, pacitane, parkan, parkinsan, peragit, romparkin, trihetphenidili hydrochloridum, trihexyphenidyl hydrochloride, triphenidyl). The international name is trihexyphenidyl. White fine crystalline powder. Slightly soluble in water, slowly soluble in alcohol. The active substance is trihexyphenidyl hydrochloride. Tablets 0.002 and 0.005 g. At a high dosage, theRead More